SYNTHESIS AND STABILITY STUDY ON AN ASPIRIN DERIVATIVE WITH POTENTIAL SELECTIVE COX-2 INHIBITOR
نویسندگان
چکیده
منابع مشابه
The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis.
Sphingolipids such as ceramides (Cers) play important roles in cell proliferation, apoptosis, and cell cycle regulation. An increased Cer level is linked to the cytotoxic effects of several chemotherapeutics. Various selective cyclooxygenase-2 (COX-2) inhibitors induce anti-proliferative effects in tumor cells. We addressed the possible interaction of the selective COX-2 inhibitors, coxibs, wit...
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ژورنال
عنوان ژورنال: Biochemistry Letters
سال: 2008
ISSN: 1687-4773
DOI: 10.21608/blj.2008.64445